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Potassium canrenoate
CAS No. 2181-04-6
Potassium canrenoate( Canrenoate potassium | SC 14266 | SC-14266 )
Catalog No. M17721 CAS No. 2181-04-6
Potassium canrenoate is a synthetic pregnadiene derivative with anti-aldosterone activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 26 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePotassium canrenoate
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NoteResearch use only, not for human use.
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Brief DescriptionPotassium canrenoate is a synthetic pregnadiene derivative with anti-aldosterone activity.
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DescriptionCanrenoate potassium is a synthetic pregnadiene derivative with anti-aldosterone activity.(In Vivo):Potassium canrenoate has been shown to cause in rats a dose-dependent increase in myelogenous leukemia and statistically significant increases in malignant tumor of the liver, thyroid, brain and mammary gland.Potassium canrenoate (20 mg/kg/day; drinking water) reduces isoprenaline-induced cardiac fibrosis in the rat.
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In Vitro——
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In VivoPotassium canrenoate has been shown to cause in rats a dose-dependent increase in myelogenous leukemia and statistically significant increases in malignant tumor of the liver, thyroid, brain and mammary gland.Potassium canrenoate (20 mg/kg/day; drinking water) reduces isoprenaline-induced cardiac fibrosis in the rat.
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SynonymsCanrenoate potassium | SC 14266 | SC-14266
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PathwayGPCR/G Protein
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TargetS1P Receptor
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RecptorMineralocorticoid Receptor
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Research AreaEndocrinology
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Indication——
Chemical Information
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CAS Number2181-04-6
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Formula Weight396.56
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Molecular FormulaC22H29KO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 100 mg/mL (252.17 mM)
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SMILES[K+].C(=O)(CC[C@@]1(CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@@]4([C@H]3CC[C@]12C)C)O)[O-]
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Chemical Name17-alpha-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, monopotassium salt
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Alexandre J, et al. J Cardiovasc Pharmacol Ther. 2015 May;20(3):313-21.
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